Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
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Management of essential hypertension
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Treatment of angina pectoris
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Prevention of cardiovascular complications related to high blood pressure
Pharmacology:
Isradipine is a dihydropyridine calcium channel blocker that inhibits calcium ion influx into vascular smooth muscle and cardiac muscle cells, causing vasodilation and decreased peripheral vascular resistance. This results in lowered blood pressure and reduced cardiac workload.
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Onset: 1–2 hours
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Duration: 12–24 hours
Dosage & Administration:
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Initial dose: 5 mg once daily
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Dose may be adjusted based on blood pressure response, typically 2.5–10 mg daily in divided doses
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Take with or without food
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Swallow whole with water
Interaction:
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May enhance effects of other antihypertensives
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Caution with beta-blockers and CYP3A4 inhibitors or inducers
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Avoid grapefruit juice as it may increase blood levels
Contraindications:
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Known hypersensitivity to Isradipine or other dihydropyridines
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Severe hypotension
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Cardiogenic shock or unstable angina
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Pregnancy and lactation unless clearly necessary
Side Effects:
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Common: Headache, dizziness, flushing, peripheral edema
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Less common: Palpitations, fatigue, nausea
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Rare: Hypotension, tachycardia, allergic reactions
Pregnancy & Lactation:
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Pregnancy: Use only if clearly needed; consult physician
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Lactation: Safety not well established; consult healthcare provider
Precautions & Warnings:
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Monitor blood pressure regularly
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Use cautiously in patients with heart failure or liver impairment
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Avoid sudden discontinuation
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Inform doctor about any adverse symptoms
Therapeutic Class:
Calcium Channel Blockers (Dihydropyridines)
Storage Conditions:
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Store in a cool, dry place below 25°C
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Protect from moisture and light
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Keep out of reach of children
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Do not use after expiry date
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