Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
ACIFIX 20 MG is indicated for the treatment of:
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Gastroesophageal reflux disease (GERD)
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Peptic ulcers
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Zollinger-Ellison syndrome
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Erosive esophagitis
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NSAID-induced gastric ulcers
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H. pylori eradication therapy (as part of combination)
Pharmacology:
Esomeprazole is the S-isomer of omeprazole and a proton pump inhibitor (PPI). It blocks the final step in acid production by inhibiting the H+/K+ ATPase enzyme in gastric parietal cells, thereby reducing gastric acidity and allowing healing of acid-induced inflammation.
Dosage:
Adults: Usually 20 mg once daily for 4–8 weeks.
Dose may vary based on the condition and physician’s advice.
Maintenance therapy may be continued at 20 mg daily.
Administration:
To be taken at least 1 hour before meals.
Swallow whole with water. Do not chew or crush the tablet.
Interaction:
May interact with drugs like ketoconazole, atazanavir, clopidogrel, diazepam, and warfarin.
Prolonged use may affect absorption of vitamin B12 and magnesium.
Contraindications:
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Hypersensitivity to esomeprazole, substituted benzimidazoles, or any component of the formulation
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Not for immediate relief of heartburn symptoms
Side Effects:
Common: Headache, nausea, diarrhea, abdominal pain, flatulence
Rare: Vitamin B12 deficiency, low magnesium, risk of bone fractures with long-term use
Pregnancy & Lactation:
Classified as Pregnancy Category B.
Use during pregnancy only if clearly needed.
Caution advised during lactation.
Precautions & Warnings:
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Prolonged use may lead to gastric malignancy masking
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Monitor magnesium and B12 with long-term use
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Use with caution in liver-impaired patients
Therapeutic Class:
Proton Pump Inhibitors (PPIs)
Storage Conditions:
Store below 30°C in a dry place, away from light and moisture.
Keep out of reach of children.
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