Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
GLIPITA M 50/1000MG is indicated for treatment of type 2 diabetes mellitus, particularly when diet, exercise, and monotherapy are insufficient to achieve adequate glycemic control.
Pharmacology:
GLIPITA M combines two antidiabetic agents: glipizide, a sulfonylurea that stimulates pancreatic insulin secretion, and metformin, a biguanide that decreases hepatic glucose production and improves insulin sensitivity.
Dosage:
Dosage must be individualized. Typically taken twice daily with meals to reduce gastrointestinal side effects. Dose adjustments depend on glycemic response and patient tolerance.
Administration:
Oral use, swallowed whole with water preferably during or after meals to minimize GI upset.
Interaction:
Possible interactions with other antidiabetics, diuretics, corticosteroids, beta-blockers, and alcohol which can affect blood glucose control.
Contraindications:
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Type 1 diabetes mellitus
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Diabetic ketoacidosis
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Severe renal or hepatic impairment
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Hypersensitivity to glipizide, metformin, or their excipients
Side Effects:
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Hypoglycemia (due to glipizide)
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Gastrointestinal disturbances (due to metformin) like nausea, vomiting, diarrhea
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Weight gain
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Rare lactic acidosis (metformin)
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Allergic reactions
Pregnancy & Lactation:
Use only if clearly needed under medical supervision. Limited safety data available; insulin preferred during pregnancy.
Precautions & Warnings:
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Monitor blood glucose and renal function regularly
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Avoid alcohol consumption
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Use caution in patients with liver or kidney disease
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Stop before surgery or contrast imaging involving iodine to prevent lactic acidosis
Therapeutic Class:
Oral hypoglycemic agent – Combination of sulfonylurea and biguanide
Storage Conditions:
Store in a cool, dry place below 30°C, away from moisture and direct sunlight. Keep out of reach of children.
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