Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
CARNOVAS 5MG is indicated for:
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Management of essential hypertension (high blood pressure).
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Adjunct therapy in stable heart failure to improve cardiac function.
Pharmacology
Nebivolol is a selective beta-1 adrenergic receptor blocker with vasodilatory properties. It reduces heart rate and cardiac output while enhancing nitric oxide-mediated vasodilation, leading to decreased vascular resistance and better blood flow.
Dosage and Administration
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Recommended dose: 5 mg once daily.
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May be adjusted based on individual response and clinical condition.
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Can be taken with or without food at a consistent time each day.
Interaction
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Increased risk of bradycardia with digoxin or other beta-blockers.
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Potentiates the hypotensive effects of antihypertensives, diuretics, or alcohol.
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Use caution with CYP2D6 inhibitors (e.g., fluoxetine), which may increase Nebivolol levels.
Contraindications
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Severe bradycardia or heart block.
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Cardiogenic shock or severe decompensated heart failure.
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Known hypersensitivity to Nebivolol or any excipient in the formulation.
Side Effects
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Common: Dizziness, fatigue, headache, and nausea.
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Rare: Hypotension, bradycardia, or allergic reactions.
Pregnancy & Lactation
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Use during pregnancy only if absolutely necessary and under medical supervision.
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Avoid during breastfeeding unless specifically advised by a physician.
Precautions & Warnings
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Gradual tapering is required to discontinue therapy to avoid rebound hypertension or angina.
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Monitor closely in patients with diabetes, as it may mask symptoms of hypoglycemia.
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Use with caution in patients with respiratory disorders, such as asthma or COPD.
Therapeutic Class
Beta-blocker, Antihypertensive agent.
Storage Conditions
Store below 30°C in a dry, cool place. Protect from light and moisture. Keep out of reach of children.
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