Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
ARIXON 2GM Injection IV is indicated for:
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Treatment of severe bacterial infections caused by susceptible microorganisms.
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Respiratory tract infections such as pneumonia and bronchitis.
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Skin and soft tissue infections.
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Urinary tract infections (UTIs).
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Bone and joint infections.
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Abdominal infections, including peritonitis.
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Septicemia and bacterial meningitis.
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Surgical prophylaxis to prevent postoperative infections.
Pharmacology:
Arixon (Ceftriaxone) is a third-generation cephalosporin antibiotic:
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It disrupts bacterial cell wall synthesis by binding to penicillin-binding proteins, leading to bacterial cell death.
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Demonstrates excellent activity against a wide range of gram-positive and gram-negative organisms.
Dosage & Administration:
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Adults: 1-2 gm once daily, depending on the severity and type of infection. For life-threatening infections, up to 4 gm daily may be used.
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Children: Dose based on weight, typically 20-80 mg/kg/day.
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Administration: Administered via intravenous (IV) infusion over 30 minutes.
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Dosage adjustment may be necessary for patients with renal or hepatic impairment.
Interaction:
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Avoid mixing or administering with calcium-containing solutions (e.g., Ringer’s solution).
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Use cautiously with nephrotoxic or ototoxic drugs.
Contraindications:
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Hypersensitivity to ceftriaxone, cephalosporins, or penicillins.
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Neonates (≤28 days) receiving calcium-containing IV solutions due to risk of precipitation.
Side Effects:
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Common: Injection site pain, diarrhea, mild rash.
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Serious: Anaphylaxis, pseudomembranous colitis, severe hypersensitivity reactions.
Pregnancy & Lactation:
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Pregnancy Category B: Safe for use under physician guidance.
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Excreted in small amounts in breast milk; use with caution during breastfeeding.
Precautions & Warnings:
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Perform appropriate culture and sensitivity tests before initiating therapy.
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Prolonged use may result in superinfection.
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Use with caution in patients with a history of colitis or other gastrointestinal disorders.
Therapeutic Class:
Third-generation cephalosporins.
Storage Conditions:
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Store below 25°C in a dry place away from light.
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Use immediately after reconstitution; discard unused portions.
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Keep out of reach of children.
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