Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Management of Type 2 Diabetes Mellitus
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Adjunct to diet and exercise
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Especially useful in overweight or insulin-resistant patients
Pharmacology:
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Dapagliflozin: An SGLT2 inhibitor that lowers blood glucose by preventing glucose reabsorption in the kidneys, leading to urinary glucose excretion.
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Metformin (850 mg): A biguanide that reduces hepatic glucose production and improves insulin sensitivity, thus helping to control fasting and postprandial glucose levels.
Dosage:
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Commonly 1 tablet once or twice daily, as prescribed by a physician
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Dose adjustments depend on individual glycemic response and tolerance
Administration:
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Take orally with meals to minimize gastrointestinal side effects
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Swallow whole with water; do not crush or chew
Interaction:
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Risk of hypoglycemia when used with insulin or sulfonylureas
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Use caution with alcohol and drugs affecting renal function
Contraindications:
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Type 1 Diabetes
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Diabetic ketoacidosis
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Severe renal impairment (eGFR <30 mL/min/1.73 m²)
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Known hypersensitivity to any ingredient
Side Effects:
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Common: Genital infections, UTI, nausea, bloating
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Rare: Lactic acidosis, hypotension, dehydration
Pregnancy & Lactation:
Use only if clearly needed and under medical supervision. Not recommended while breastfeeding without physician’s advice.
Precautions & Warnings:
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Monitor renal function before and during therapy
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Ensure adequate hydration
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Temporarily discontinue during acute illness, surgery, or radiologic procedures with contrast
Therapeutic Class:
Oral Antidiabetic Combination (SGLT2 inhibitor + Biguanide)
Storage Conditions:
Store in a cool and dry place below 30°C. Protect from moisture and light. Keep out of reach of children.
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