Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
ATOVA EZ 10/10 MG Tablet is indicated for:
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Hypercholesterolemia (high LDL cholesterol) management in adults and children.
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Mixed dyslipidemia with elevated LDL, triglycerides, and low HDL.
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Cardiovascular risk reduction for individuals with heart conditions or multiple risk factors.
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Familial hypercholesterolemia treatment.
Pharmacology:
ATOVA EZ combines two active agents for comprehensive cholesterol management:
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Atorvastatin (10mg): An HMG-CoA reductase inhibitor that lowers LDL cholesterol by inhibiting hepatic cholesterol synthesis and enhances HDL cholesterol.
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Ezetimibe (10mg): A cholesterol absorption inhibitor that prevents intestinal cholesterol uptake, complementing the effects of Atorvastatin.
This synergistic combination results in significant lipid profile improvement and reduced cardiovascular risks.
Dosage & Administration:
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Adults: One tablet daily, preferably at the same time each day. Dosage adjustments should follow lipid profile evaluations.
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Children (>10 years): As directed by a physician, typically one tablet daily.
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May be taken with or without food.
Interaction:
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Concomitant use with fibrates or niacin increases muscle toxicity risk.
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Grapefruit juice may enhance Atorvastatin levels; intake should be limited.
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Ezetimibe’s efficacy may be reduced when taken with bile acid sequestrants.
Contraindications:
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Hypersensitivity to Atorvastatin, Ezetimibe, or their components.
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Active liver disease or persistent elevation of liver enzymes.
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Pregnancy and lactation.
Side Effects:
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Common: Nausea, headache, abdominal discomfort, muscle pain, diarrhea.
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Rare: Rhabdomyolysis, severe muscle damage, liver enzyme elevation, allergic reactions.
Pregnancy & Lactation:
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Pregnancy: Category X - Not recommended as it may harm fetal development.
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Lactation: Contraindicated due to possible passage into breast milk.
Precautions & Warnings:
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Regular monitoring of liver enzymes and lipid profile is necessary.
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Discontinue use if unexplained muscle pain or weakness occurs.
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Use cautiously in patients with liver disease history or excessive alcohol consumption.
Therapeutic Class:
Lipid-lowering agents (Statin + Cholesterol absorption inhibitor).
Storage Conditions:
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Store in a cool, dry place below 25°C.
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Protect from light and moisture.
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Keep out of reach of children.
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