Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
ATOVA EZ 20/10 MG Tablet is indicated for:
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Patients with hypercholesterolemia (high LDL cholesterol) not controlled by diet alone.
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Mixed dyslipidemia with elevated LDL and triglycerides, and low HDL.
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Cardiovascular risk reduction in patients with existing heart conditions or multiple risk factors.
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Treatment of familial hypercholesterolemia.
Pharmacology:
ATOVA EZ contains a combination of:
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Atorvastatin (20mg): An HMG-CoA reductase inhibitor that reduces cholesterol synthesis in the liver, lowers LDL cholesterol, and increases HDL cholesterol.
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Ezetimibe (10mg): Inhibits cholesterol absorption in the intestines, complementing Atorvastatin’s action for enhanced cholesterol reduction.
This dual mechanism effectively improves lipid profiles, reducing cardiovascular risks.
Dosage & Administration:
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Adults: One tablet daily, taken with or without food. Dosage adjustments may depend on lipid profile response.
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Children (>10 years): As prescribed by the physician, typically a lower dose.
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Administer at a consistent time each day for optimal results.
Interaction:
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Increased risk of muscle toxicity when used with fibrates or niacin.
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Grapefruit juice should be avoided as it may elevate atorvastatin levels.
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Ezetimibe may interact with bile acid sequestrants, reducing its efficacy.
Contraindications:
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Hypersensitivity to Atorvastatin, Ezetimibe, or any excipients in the formulation.
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Active liver disease or unexplained persistent elevations in liver enzymes.
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Pregnancy and lactation.
Side Effects:
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Common: Headache, nausea, muscle pain, diarrhea, abdominal pain.
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Rare: Rhabdomyolysis, severe muscle damage, elevated liver enzymes, allergic reactions.
Pregnancy & Lactation:
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Pregnancy: Contraindicated (Category X) as it may harm fetal development.
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Lactation: Avoid use due to the potential passage of the drug into breast milk.
Precautions & Warnings:
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Regularly monitor liver function and lipid profile.
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Stop immediately if unexplained muscle pain, weakness, or tenderness occurs.
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Use cautiously in patients with a history of liver disease or excessive alcohol consumption.
Therapeutic Class:
Lipid-lowering agents (Statin + Cholesterol absorption inhibitor).
Storage Conditions:
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Store in a cool, dry place below 25°C.
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Protect from light and moisture.
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Keep out of reach of children.
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