Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Amdocal Plus 25mg is indicated for:
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Essential hypertension
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Hypertension with coexisting angina
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Hypertension in patients requiring combination therapy
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Cardiovascular risk reduction in hypertensive patients
Pharmacology:
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Amlodipine: A long-acting calcium channel blocker that dilates blood vessels, lowering peripheral resistance and blood pressure.
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Atenolol: A cardioselective beta-1 blocker that reduces heart rate, cardiac output, and blood pressure, and is effective in preventing angina.
Their combination offers synergistic effects in controlling blood pressure and reducing the workload on the heart.
Dosage:
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Usual adult dose: 1 tablet once daily
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Dose adjustment may be needed based on blood pressure response
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Not recommended in severe renal impairment or bradycardia without physician's advice
Administration:
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Take orally with water
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Can be taken with or without food
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Best taken at the same time each day
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Do not skip or stop abruptly without doctor consultation
Interaction:
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Caution with other antihypertensives (additive effect)
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May interact with NSAIDs (reduced antihypertensive effect)
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Avoid with verapamil or diltiazem (risk of bradycardia)
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May enhance blood sugar masking effect in diabetics
Contraindications:
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Hypersensitivity to Amlodipine or Atenolol
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Bradycardia, heart block, or cardiogenic shock
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Severe hypotension
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Asthma or bronchospastic disease (due to beta-blocker)
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Untreated pheochromocytoma
Side Effects:
Common: Fatigue, dizziness, bradycardia, cold extremities, edema
Less common: Nausea, constipation, headache, hypotension
Rare: Heart block, shortness of breath, allergic reactions
Pregnancy & Lactation:
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Pregnancy Category C/D (Atenolol may affect fetal growth)
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Not recommended during pregnancy unless absolutely necessary
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Use caution while breastfeeding
Precautions & Warnings:
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Monitor heart rate and blood pressure regularly
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Use cautiously in patients with diabetes, asthma, or kidney disease
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Do not discontinue abruptly – may cause rebound hypertension or angina
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May cause dizziness—avoid driving at the beginning of therapy
Therapeutic Class:
Combined antihypertensive (Calcium Channel Blocker + Beta-blocker)
Storage Conditions:
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Store below 30°C
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Protect from light and moisture
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Keep out of reach of children
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