Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Amdocal Plus 50mg is indicated for:
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Moderate to severe essential hypertension
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Hypertension associated with angina
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Patients requiring combination therapy for better BP control
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Secondary prevention of cardiovascular events
Pharmacology:
This combination includes:
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Amlodipine: A calcium channel blocker that inhibits calcium influx into vascular smooth muscles, resulting in vasodilation and reduced blood pressure.
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Atenolol (50mg): A cardioselective beta-blocker that reduces heart rate and cardiac workload, helping to manage hypertension and prevent angina.
Together, they provide additive antihypertensive effects.
Dosage:
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Recommended dose: 1 tablet once daily
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Dose adjustment based on patient response and tolerability
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Not suitable for patients with severe renal, hepatic, or cardiac dysfunction without medical advice
Administration:
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Taken orally once daily
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Can be taken with or without meals
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Swallow whole with water
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Avoid skipping or doubling doses
Interaction:
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Potentiated effect when used with other antihypertensives
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May interact with NSAIDs (reducing BP-lowering effect)
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Caution with antiarrhythmics, insulin, or antidiabetics
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Avoid combining with calcium channel blockers like verapamil
Contraindications:
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Hypersensitivity to amlodipine or atenolol
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Bradycardia, 2nd or 3rd-degree heart block
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Cardiogenic shock or overt heart failure
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Asthma or COPD (due to atenolol)
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Pregnancy or lactation without physician supervision
Side Effects:
Common: Fatigue, bradycardia, ankle swelling, dizziness
Less common: Cold extremities, sleep disturbance, GI upset
Rare: Bronchospasm, AV block, skin rash
Pregnancy & Lactation:
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Pregnancy Category D (risk to fetus especially in 2nd/3rd trimester)
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Not recommended during pregnancy unless no alternatives exist
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Caution advised while breastfeeding; atenolol may pass into milk
Precautions & Warnings:
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Monitor BP, HR, and renal function regularly
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Caution in diabetic patients—may mask signs of hypoglycemia
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Gradual withdrawal is advised to avoid rebound hypertension
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May cause dizziness or fatigue—caution during driving
Therapeutic Class:
Antihypertensive combination (Calcium Channel Blocker + Beta-blocker)
Storage Conditions:
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Store below 30°C
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Keep in a cool, dry place
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Protect from light and moisture
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Keep out of reach of children
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